Spectroscopy instructs scientists, technicians, and laboratory managers in the efficient, productive use of spectroscopic instruments, and promotes the acceptance of spectroscopy as a practical analytical technology in industry and life science. We serve subscribers by publishing a highly focused editorial product that combines peer-reviewed scientific articles with practical, solutions-based information, helping them to become better spectroscopists whether they work in the laboratory, on the process line, or in the field. |  |
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| Dangerous Toys: Rigid Testing Routines Required to Assure Our Children's Safety
|  | | | | Ultraviolet Signals in Blue Tits
| | | | The Importance of Using Correct Sampling Procedures in Obtaining
| | Retsch, Inc. | | | Miniature Spectrometers: Preventive Maintenance and Calibration
| | Ocean Optics, Inc. | | | Low-Frequency and Stokes-Antistoke Raman Measurements Using TriVista
| | R. Shafer, O. Rohm, Spectroscopy & Imaging GMBH; D. Koulikov, A. O?Grady, Princeton Instruments/Acton Research | | | Measurement of the Spectroscopic Properties of Optical Components for CD-DVD Players Using the Microsample Measurement Accessory
| | Stephen T. Watts, Kazuyo Miura, and Takayuki Wakui, Hitachi High Technologies America, Inc. |
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| Wilhelm Conrad Röntgen and the Discovery of X-Rays
| | Volker Thomsen takes a look at the impact that the discovery of X-rays by Wilhelm Röntgen in 1895 has had on the world. | | | A Pragmatic Approach to Managing Interferences in ICP-MS
| | While inductively coupled plasma-mass spectrometry (ICP-MS) is capable of part-per-quadrillion (ppq) detection limits under ideal conditions, most applications do not require this level of sensitivity and do not justify the cost associated with achieving it. Practical sensitivity in ICP-MS is determined not by instrument signal-to-noise ratio, but rather by controlling interferences and matrix effects in real samples. Understanding the sources of these effects and their management is critical in determining the most practical way to achieve specific data quality objectives. | | | Innovations in Speciation Analysis Using HPLC with ICP-MS Detection
| | Speciation analysis has grown rapidly and has expanded to a variety of markets, including environmental, clinical, food, nutraceutical, and bioanalytical. This growth has resulted from the realization that knowing the total amount of an element does not always provide adequate information for assessing health and environmental effects, but knowing which form of the element is present presents a much more comprehensive picture. | | | RoHS/WEEE Application of a Miniature X-Ray Spectrometer
| | The RoHS/WEEE directive requires the electronics industry to certify that products comply with maximum concentration amounts of particular elements and compounds (Cr VI, Pb, Cd, Hg, Br PBB/PBDE) by July 2006. Instrumentation must be developed to perform the certification. | | | Quantitative Analysis of Low Levels of Chlorine and Iron in Hydraulic Oil Samples
| | Simple, fast, and reliable on-site hydraulic oil analysis should be an integral part of any preventative maintenance program. Since the majority of machine failures are contamination related, it is important to analyze the hydraulic fluid to monitor equipment condition and identify machine wear. Significant cost savings can result from early identification of machine failure, oil quality, handling and other problems. Oil analysis can detect changes in oil quality, contamination, wear and chemical differences. Benefits of this information include prolonged equipment life, reduced equipment downtime, and reduced overall maintenance costs. In addition, plants can increase intervals between oil changes, thus reducing waste oil, maintenance, and oil purchase costs. | | | MORE ARTICLES
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| Miniature Optical Spectrometers: Follow the Money Part II: The Telecommunications Boom
| | The author examines NIR spectrometers and the technologies developed during the telecommunications boom of the late 1990s, focusing on miniaturized optical techniques generally called MOEMS. | | | Probing the Structural Effects of Pasteurization and Spray Drying on Soy Protein Isolate in the Presence of Trehalose Using FT-IR-ATR and FT-Raman Spectroscopy
| | The authors present the results of a study in which FT-IR-ATR and FT-Raman spectrosopies were used to probe the effects of pasteurization and spray drying on the secondary structure of soy protein isolate. | | | Surface-Enhanced Nanosensors
| | January 2007. This review article summarizes biological applications that utilize surface plasmon resonance, localized surface plasmon resonance, and surface-enhanced Raman spectroscopy. | | | Analysis of Volatile Bacterial Metabolites by Gas Chromatography-Mass Spectrometry
| | Here the authors describe a new method for the identification of key volatile organic compound markers using mass spectrometry combined with gas chromatography. | | | Measurement of Metabolic Stability Using SIM and Identification of Metabolites by Data-Dependent full-Scan MS-MS and CNL Scanning
| | In this article, the role of a triple-quadrupole mass spectrometer in performing in vitro studies of compound metabolic stability and identification of Phase I and II metabolites is demonstrated. | | | Infrared Tissue Imaging Applications Growing in Biomedical Research and Diagnosis
| | IR imaging provides a new tool for disease detection, revealing compositional and structural information in tissue previously not available with contrast staining. | | | Measurement of the Dynamic Rates of Association and Dissociation of EGF with its Cell-surface Receptor in Intact Cells
| | Many important biological signals are triggered by the binding of a peptide hormone to its cognate receptor at the cell surface. Using stopped-flow fluorescence spectroscopy, the authors have been able to observe, in real time, ligand binding to epidermal growth factor receptors expressed at the surface of intact cells. This method allows for the measurement of kinetic association and dissociation rates with high data density in a native cellular environment, providing insights into the signal-initiation process in this system that have not been revealed through the determination of ligand-binding constants obtained by more traditional methods. | | | ICP-MS Speciation Analysis: Three Roles of Selenium
| | The element selenium plays three distinct roles in biological processes, functioning in turn as a toxicant, a chemopreventive agent, and a heavy metal antagonist. This article discusses current research associated with each role, and how ICP-MS can be employed to better understand and utilize selenium's properties. | | | Influence of Na+ and K+ Concentration in solvents on Mass Spectra of Peptides in LC–ESI-MS
| | The concentration dependent influence of Na+ and K+ions on mass spectra of peptides is shown with human gastrin as a model peptide. With electrospray ionization the doubly charged protonated molecule ion [M+2H]2+ is normally the preferred ionization product. However, trace amounts of alkali metal ions already form clusters (adducts) with the peptide molecule, such as [M+H+Na]2+, which become dominating at higher concentrations. With Na+/K+ concentrations below 0.1 mg/kg (ppm) only a few clusters appear, which allow the correct doubly charged molecule ion to be assigned for a subsequent MS–MS experiment. With concentrations of 10 ppm and higher the alkali clusters become the most abundant peaks in the spectrum, and the absolute sensitivity is decreased by a factor of 5–10. Experiments were performed with water and water–methanol mixtures with a known Na+/K+ +content. | | | MORE ARTICLES
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